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Radiation Therapy

SCART radiation therapy for Cancer

Phase 1
Waitlist Available
Research Sponsored by Baptist Health, Louisville
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3-6 months
Awards & highlights
No Placebo-Only Group

Summary

We aim to evaluate the feasibility and toxicity of testing the tolerance and immunogenic effects of high-dose SCART radiotherapy in patients with bulky metastatic or recurrent cancer in the setting of a single-arm phase I clinical trial. The primary endpoint of the study was to determine dose-limiting toxicities (DLT)s and the Maximum Tolerated Dose (MTD) of SCART to bulky metastatic or recurrent cancers.

Eligible Conditions
  • Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3-6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3-6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Toxicity
Secondary study objectives
Assessment of the antitumor effect
Biomarkers
Evaluation of quality of life (QoL).

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: SCART ArmExperimental Treatment1 Intervention
Single Arm patients will be treated with SCART to different dose levels.

Find a Location

Who is running the clinical trial?

Baptist Health, LouisvilleLead Sponsor
4 Previous Clinical Trials
1,791 Total Patients Enrolled
Drexel UniversityOTHER
154 Previous Clinical Trials
48,194 Total Patients Enrolled
Innovative InstituteUNKNOWN
~3 spots leftby Nov 2025
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