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Cancer Imaging Agent

[18F]-FAPI-74 PET/ MRI for Dermatomyositis (FAPI-74 Trial)

Phase 2
Waitlist Available
Research Sponsored by Farshad Moradi
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
1. Patients with suspected dermatomyositis.
2. Patient must be \> 18 years old.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 1 hour
Awards & highlights

Summary

This study proposes the use of a PET isotope, \[18F\]-Fibroblast Activation Protein Inhibitor-74, for a prospective single-center, single-arm study using MRI imaging for participants with Refractory Dermatomyostitis.

Who is the study for?
This trial is for individuals with refractory dermatomyositis, a condition where standard treatments haven't worked. Participants must meet certain health criteria to be included, but specific inclusion and exclusion details are not provided in the given information.
What is being tested?
[18F]-FAPI-74 PET/MRI imaging is being tested in this study. It's a single-center, single-arm trial which means all participants will receive the same intervention without comparison to another group or treatment.
What are the potential side effects?
Potential side effects of [18F]-FAPI-74 PET/MRI imaging are not detailed in the provided information. Generally, PET scans have minimal side effects related to exposure to radioactive tracers.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 1 hour
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 hour for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Rate of [18F]-FAPI-74 uptake.

Trial Design

1Treatment groups
Experimental Treatment
Group I: [18F]-FAPI-74 PET/ MRIExperimental Treatment1 Intervention
Participant receive \[18F\]-FAPI-74 injection and approximately 45-60 minutes later receive a MRI scan from vertex to legs, followed by a static PET emission scan over the same area.

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Who is running the clinical trial?

Farshad MoradiLead Sponsor
~14 spots leftby Oct 2027
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