Growth Hormone Injections for Knee Osteoarthritis

Phase 2

Waitlist Available

Led By John Sledge, MD

Research Sponsored by John Sledge

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the grade will be assigned at 3 time points: before the first injection, immediately before the 6th injection, and one hour after the 6th injection.

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to test if growth hormone injections can help treat knee osteoarthritis. The injections may stimulate cartilage growth, reduce pain and stiffness, and improve mobility in the knee. Participants will

Who is the study for?

This trial is for individuals with osteoarthritis in the knee. Participants should be willing to receive weekly growth hormone injections directly into their knee joint over a six-week period and follow up with exercises, X-rays, and clinic visits.

What is being tested?

The study tests if injecting human growth hormone into the knee stimulates cartilage growth, reduces pain and stiffness, and improves mobility. Progress is monitored through X-rays, physical evaluations, questionnaires on treatment effects.

What are the potential side effects?

Potential side effects may include discomfort at injection site, swelling or stiffness in the treated knee. Since it's an investigational treatment, other unexpected side effects could occur.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the grade will be assigned at 3 time points: before the first injection, immediately before the 6th injection, and one hour after the 6th injection.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the grade will be assigned at 3 time points: before the first injection, immediately before the 6th injection, and one hour after the 6th injection.

This trial's timeline: 3 weeks for screening, Varies for treatment, and the grade will be assigned at 3 time points: before the first injection, immediately before the 6th injection, and one hour after the 6th injection. for reporting.