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DESTRESS-T for Post-Traumatic Stress Disorder (DESTRESS-T Trial)

N/A
Waitlist Available
Led By COL Charles C. Engel, MD, MPH
Research Sponsored by Uniformed Services University of the Health Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 12 week, 18 week and 24 week
Awards & highlights

Summary

This study will evaluate a telephone-delivered cognitive-behavioral psychotherapy intervention designed for primary care treatment of combat-exposed service members with PTSD. The investigators will assess Posttraumatic Stress Disorder (PTSD) symptoms, mental health-related and occupational functioning, and symptoms of depression, anxiety, and somatization.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Posttraumatic Stress Disorder Checklist - Civilian Version (PCL)
Secondary study objectives
Alcohol Use Disorders Identification Test-Civilian version (AUDIT-C)
Generalized Anxiety Symptom Severity (GAD-7)
Medical Outcomes Survey Short-Form-12 (SF-12)
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: DESTRESS-TExperimental Treatment1 Intervention
Usual primary care PTSD treatment, plus a telephone care management program over 8 weeks that includes: four outreach calls, feedback to the treating primary care provider, and care coordination
Group II: Optimized Usual Care (OUC)Active Control1 Intervention
Optimized Usual Care is usual primary care PTSD treatment, plus a telephone care management program that includes: four outreach calls, feedback to the treating primary care provider (PCP), and care coordination.

Find a Location

Who is running the clinical trial?

Walter Reed National Military Medical CenterFED
138 Previous Clinical Trials
32,897 Total Patients Enrolled
United States Department of DefenseFED
891 Previous Clinical Trials
332,387 Total Patients Enrolled
US Department of Veterans AffairsFED
872 Previous Clinical Trials
497,898 Total Patients Enrolled
~7 spots leftby Sep 2025