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Preventative Skin Care for Pediatric Brain Cancer

Phase 2
Waitlist Available
Led By Jennifer Huang, MD
Research Sponsored by Dana-Farber Cancer Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosed with a brain tumor between ages 6 months old -18 years old and will undergo treatment with at least one of the following: Targeted BRAF inhibitor therapy, Targeted MEK inhibitor therapy, Targeted pan-RAF inhibitor therapy
Be younger than 65 years old
Must not have
Diagnosed with brain tumor at > 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Summary

This trial tests a skin care routine for children with brain tumors undergoing cancer treatments. The routine includes gentle skin care, sun protection, and bleach baths. It aims to reduce skin problems caused by the treatments.

Who is the study for?
This trial is for children aged 6 months to 18 years with a brain tumor, who will be treated with specific targeted therapies (BRAF, MEK, or pan-RAF inhibitors). They must be able to follow a skin care routine including sun protection and bleach baths. Children with allergies to sunscreen or skincare products used in the study cannot participate.
What is being tested?
The study tests whether a preventive skin care regimen can help children undergoing treatment for brain tumors with certain inhibitors. The regimen includes dilute bleach baths, high SPF sunscreen, moisturizers, protective clothing, and limited sun exposure.
What are the potential side effects?
Potential side effects may include skin irritation from the bleach baths or allergic reactions to the skincare products like sunscreen and moisturizers. Sunscreen might also cause discomfort if there's an existing sensitivity.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I was diagnosed with a brain tumor as a child and will be treated with targeted therapy.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I was diagnosed with a brain tumor as an adult.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Rate of Cutaneous Reaction
Secondary study objectives
Children's Dermatology Quality of life
Hand foot syndrome Severity
Overall Cutaneous Reaction Severity
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Preventative Skin Care RoutineExperimental Treatment6 Interventions
Participants will perform a preventative skin care routine that includes daily sun protection, daily gentle skin care and every-other-day dilute bleach baths for the duration of the study. Participants will receive skin examinations and complete a survey about their skin condition at the initial visit when anti-cancer treatment is started, at six weeks after the start of treatment, and at twelve weeks after the start of treatment.

Find a Location

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor
1,100 Previous Clinical Trials
353,077 Total Patients Enrolled
Jennifer Huang, MD3.04 ReviewsPrincipal Investigator - Boston Children's Hospital
Dana-Farber Cancer Institute
2 Previous Clinical Trials
12 Total Patients Enrolled
1Patient Review
Will give you a severe diagnosis to scare you, make you wait 3 months for an appointment, and then just tell you bug bites. Made my wife feel unintelligent for not being a native English speaker.

Media Library

Dilute bleach baths (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04479514 — Phase 2
Eczema Research Study Groups: Preventative Skin Care Routine
Eczema Clinical Trial 2023: Dilute bleach baths Highlights & Side Effects. Trial Name: NCT04479514 — Phase 2
Dilute bleach baths (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04479514 — Phase 2
~4 spots leftby Sep 2025
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