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Phosphodiesterase 4 (PDE4) inhibitor

Apremilast for Lichen Planus

Phase 2
Waitlist Available
Led By David M Pariser, MD
Research Sponsored by Virginia Clinical Research, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

This trial tests if taking an Apremilast pill regularly for a few months can improve moderate to severe lichen planus, a skin condition that doesn't respond well to other treatments. The pill works by reducing inflammation in the body. Apremilast has shown promise in treating various inflammatory conditions, including psoriasis and lichen planus.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

1Treatment groups
Experimental Treatment
Group I: ApremilastExperimental Treatment1 Intervention
Apremilast 20 mg PO administered BID over 12 weeks
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetazolamide
FDA approved

Find a Location

Who is running the clinical trial?

Virginia Clinical Research, Inc.Lead Sponsor
3 Previous Clinical Trials
139 Total Patients Enrolled
Celgene CorporationIndustry Sponsor
444 Previous Clinical Trials
58,227 Total Patients Enrolled
1 Trials studying Lichen Planus
42 Patients Enrolled for Lichen Planus
Clare E Foss, MDStudy ChairEastern Virginia Medical School
~1 spots leftby Sep 2025