← Back to Search

Unknown

TPN-101, 400 mg/day for Amyotrophic Lateral Sclerosis

Phase 2
Waitlist Available
Research Sponsored by Transposon Therapeutics, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48 weeks

Summary

This trial tests a new drug, TPN-101, for safety and tolerability in patients with ALS and/or FTD who have a specific genetic mutation. The goal is to see if it can help manage symptoms or slow disease progression.

Eligible Conditions
  • Amyotrophic Lateral Sclerosis
  • Frontotemporal Dementia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Assess the safety and tolerability of TPN-101 in patients with C9ORF72 amyotrophic lateral sclerosis (ALS)/frontotemporal dementia (FTD)
Secondary study objectives
Assess the clinical effect of TPN-101 as measured by changes in score on the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R)

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: TPN-101, 400 mg/dayExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Location

Who is running the clinical trial?

Transposon Therapeutics, Inc.Lead Sponsor
2 Previous Clinical Trials
56 Total Patients Enrolled
~10 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top