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Biological

Platelet-rich plasma for Nail Diseases

Phase 4
Waitlist Available
Led By Shari R Lipner, MD, PhD
Research Sponsored by Weill Medical College of Cornell University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 16 weeks
Awards & highlights

Summary

This trial is testing a treatment where a patient's own blood is used to help heal and strengthen weak, breakable nails. The treatment aims to use special components in the blood to repair the nails.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 16 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 16 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Physician Global Improvement Assessment (PGIA)
Secondary study objectives
Change From Baseline in Qualify of Life, as Measured by the Modified Nail Psoriasis Quality of Life Scale (NPQ10) Between Baseline and Week 16

Side effects data

From 2023 Phase 4 trial • 11 Patients • NCT04941807
30%
Subungual hematoma
20%
Onychomadesis
10%
Leukonychia
10%
Beau's line(s)
100%
80%
60%
40%
20%
0%
Study treatment Arm
Platelet-rich Plasma
Platelet-poor Plasma

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Platelet-rich plasmaExperimental Treatment1 Intervention
The proximal nail fold is cleansed with alcohol and platelet-rich plasma obtained from the patient is injected using a 1ml syringe and 30g needle, 0.1-0.2 ml of platelet-rich plasma is injected into 8 proximal nail folds.
Group II: Platelet-poor plasmaPlacebo Group1 Intervention
The proximal nail fold is cleansed with alcohol and platelet-poor plasma obtained from the patient is injected using a 1ml syringe and 30g needle, 0.1-0.2 ml of platelet-poor plasma is injected into 2 proximal nail folds.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Platelet-rich plasma
2016
Completed Phase 4
~360

Find a Location

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor
1,077 Previous Clinical Trials
1,320,656 Total Patients Enrolled
4 Trials studying Nail Diseases
31 Patients Enrolled for Nail Diseases
Eclipse Aesthetics, LLCOTHER
2 Previous Clinical Trials
70 Total Patients Enrolled
Shari R Lipner, MD, PhDPrincipal InvestigatorWeill Medical College of Cornell University
2 Previous Clinical Trials
2 Trials studying Nail Diseases
~2 spots leftby Sep 2025
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