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Device

tDCS for Alzheimer's Disease

N/A
Recruiting
Led By Carlos Roncero, PhD
Research Sponsored by Lady Davis Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Diagnosis of Alzheimer's Disease or other form of dementia (e.g., Primary Progressive Aphasia)
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up two years
Awards & highlights

Summary

This trial will study the effects of using tDCS at home for people with dementia. Some participants from previous studies are interested in buying their own tDCS machine and have asked for advice. The

Who is the study for?
This trial is for individuals with Alzheimer's Disease or other forms of dementia, such as Primary Progressive Aphasia. It's designed for those who have used tDCS in a lab setting and are interested in continuing treatment at home. Participants will be advised on purchasing their own tDCS machine and trained to use it properly.
What is being tested?
The study tests the effectiveness of Transcranial Direct Current Stimulation (tDCS) administered at home by participants with dementia. The researchers will monitor the condition of these individuals over two years through monthly reports to assess how well tDCS works outside a clinical setting.
What are the potential side effects?
While specific side effects are not detailed here, typical side effects from tDCS can include mild tingling, itching or discomfort at the site of stimulation, fatigue, headache, nausea or irritability post-treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~two years
This trial's timeline: 3 weeks for screening, Varies for treatment, and two years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
General Cognition

Side effects data

From 2021 Phase 2 & 3 trial • 160 Patients • NCT02483468
2%
skin irritation
2%
Car accident
100%
80%
60%
40%
20%
0%
Study treatment Arm
tDCS (Active)
tDCS (Sham)

Trial Design

1Treatment groups
Experimental Treatment
Group I: At Home tDCS UsersExperimental Treatment1 Intervention
Participants conducting tDCS at home
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Direct Current Stimulation
2014
Completed Phase 3
~1100

Find a Location

Who is running the clinical trial?

Lady Davis InstituteLead Sponsor
45 Previous Clinical Trials
5,600 Total Patients Enrolled
Carlos Roncero, PhDPrincipal InvestigatorBaycrest
~7 spots leftby Oct 2026
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