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Personalized Augmented Cognitive Training (PACT) for Traumatic Brain Injury (PACT Trial)

N/A
Waitlist Available
Led By Elizabeth W Twamley, PhD
Research Sponsored by Veterans Medical Research Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6, 12 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial tests a new treatment called Personalized Augmented Cognitive Training (PACT) for military members and Veterans with mild brain injuries who have ongoing symptoms. PACT involves personalized training sessions, either in-person or via video, and uses mobile apps to help improve thinking skills. The goal is to see if PACT can make it easier for these individuals to manage their symptoms and improve their daily functioning.

Eligible Conditions
  • Traumatic Brain Injury

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6, 12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6, 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in the Neurobehavioral Symptom Inventory (NSI)
Secondary study objectives
Change in California Verbal Learning Test-III (CVLT-III)
Change in Cognitive Problems and Strategies Assessment
Change in D-KEFS Verbal Fluency
+11 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: PACTExperimental Treatment1 Intervention
Personalized Augmented Cognitive Training (PACT)
Group II: ETAUActive Control1 Intervention
Enhanced Treatment As Usual (ETAU)

Find a Location

Who is running the clinical trial?

Veterans Medical Research FoundationLead Sponsor
43 Previous Clinical Trials
4,838 Total Patients Enrolled
United States Naval Medical Center, San DiegoFED
108 Previous Clinical Trials
23,044 Total Patients Enrolled
Elizabeth W Twamley, PhDPrincipal InvestigatorVeterans Medical Research Foundation
2 Previous Clinical Trials
119 Total Patients Enrolled
~16 spots leftby Nov 2025
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