What side effects are associated with this type of intervention?

Common treatments for chronic pain that involve behavioral modification and psychological principles, such as cognitive behavioral therapy (CBT), psychoeducation, and internet-based interventions, generally have minimal side effects. Some patients may experience temporary increases in distress or discomfort as they confront and work through their pain-related thoughts and behaviors. However, these interventions are typically well-tolerated and have fewer adverse effects compared to pharmacological treatments. The primary focus is on improving coping strategies, reducing pain intensity, and enhancing overall quality of life.

What prior FDA approvals exist?

The FDA has approved various treatments for chronic pain, including pharmacologic and non-pharmacologic options. While specific FDA approvals for behavioral interventions like those in the HOPE trial are less common, cognitive-behavioral therapy (CBT) and internet-delivered pain management programs have shown efficacy in clinical trials. These interventions focus on modifying behavior and psychological responses to pain, similar to the HOPE approach. Additionally, virtual reality (VR) interventions and other mind-body therapies have been explored for their potential to reduce chronic pain without relying on medications.

What other types of research exist?

Promising alternatives to the HOPE intervention for chronic pain patients include: 1) Digital Cognitive Behavioral Therapy for Insomnia (CBT-I), which has shown improvements in functional health and psychological well-being; 2) Social prescribing, which connects patients to community resources and support groups; 3) Regular exercise and physical therapy, which can improve both motor and non-motor symptoms; and 4) Technology-enhanced delivery of CBT-based interventions, such as web-based training and smartphone applications, which have shown efficacy in substance use disorders and could be adapted for chronic pain management.

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Psychology-based Intervention

HOPE Social Media Intervention for Chronic Pain

N/A

Waitlist Available

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

≥ 18 years of age

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Summary

This trial uses social media to help people with chronic pain avoid abusing prescription drugs. It targets those who are at risk of drug misuse by providing online support and helpful strategies.

Who is the study for?

This trial is for adults over 18 who are patients within the UCLA health system, have been on opioid therapy between 3 and 12 months for chronic non-cancer pain. Only those referred by their physician can join.

What is being tested?

The HOPE intervention uses social media and psychology-based strategies to help reduce prescription drug abuse in individuals with chronic pain.

What are the potential side effects?

Since this is a behavioral intervention using social media, there are no direct medical side effects like you'd expect from medication or surgery.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: interventionExperimental Treatment1 Intervention

behavioral intervention

Group II: controlActive Control1 Intervention

control

0 / 1Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for chronic pain include cognitive behavioral therapy (CBT), mindfulness-based stress reduction (MBSR), and interdisciplinary pain management. These treatments work by altering pain perception and improving coping strategies. CBT helps patients reframe negative thoughts and behaviors related to pain, while MBSR focuses on increasing awareness and acceptance of pain through meditation and mindfulness practices. Interdisciplinary pain management combines various therapeutic approaches to address the physical, emotional, and social aspects of pain. Understanding these mechanisms is crucial for chronic pain patients as it empowers them to actively participate in their treatment, potentially leading to better pain management and improved quality of life.

Can pain be managed through the Internet? A systematic review of randomized controlled trials.

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor

1,554 Previous Clinical Trials

10,264,063 Total Patients Enrolled

8 Trials studying Chronic Pain

12,769 Patients Enrolled for Chronic Pain

Media Library

HOPE Social Media Intervention (Psychology-based Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT02735785 — N/A

Chronic Pain Research Study Groups: intervention, control

Chronic Pain Clinical Trial 2023: HOPE Social Media Intervention Highlights & Side Effects. Trial Name: NCT02735785 — N/A

HOPE Social Media Intervention (Psychology-based Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02735785 — N/A

~5 spots leftby Sep 2025

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