Your session is about to expire
← Back to Search
Cancer Detection
Breath Test for Esophageal Cancer
N/A
Waitlist Available
Led By Donald E Low, MD
Research Sponsored by Benaroya Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Aged 18-90 years
Newly-diagnosed, treatment naïve patients with esophageal and/or gastroesophageal junctional cancer
Must not have
Without malignant esophageal disease
Malignancy at a secondary site other than the esophagus
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before commencing treatment for esophogeal cancer
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to see if we can detect and track esophageal cancer by analyzing a person's breath.
Who is the study for?
This trial is for adults aged 18-90 with newly-diagnosed, untreated esophageal or gastroesophageal junction cancer who are planning curative treatment including chemo, radiotherapy, and surgery. It's not for those unwilling to consent, pregnant women, patients receiving palliative care only or those with secondary cancers.
What is being tested?
The study is testing if a breath test can detect and monitor esophageal cancer by analyzing exhaled volatile organic compounds (VOCs) in patients before they undergo standard treatments.
What are the potential side effects?
Since the intervention involves a non-invasive breath test, there are no direct side effects associated with this procedure as it does not involve drugs or invasive techniques.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am between 18 and 90 years old.
Select...
I have recently been diagnosed with cancer in my esophagus or where my esophagus meets my stomach and have not started treatment.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I do not have cancer in my esophagus.
Select...
My cancer has spread to areas other than the esophagus.
Select...
I am receiving treatment to ease symptoms for esophageal cancer.
Select...
I am not undergoing treatment for esophageal cancer with chemo, radiation, and surgery.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ before commencing treatment for esophageal cancer
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before commencing treatment for esophageal cancer
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Exhaled breath and urinary VOC concentrations as biomarkers of esophageal cancer
Secondary study objectives
Changes in VOC concentrations that occur in response to therapeutic intervention
Linkage of longitudinal VOC data to predominant upper gastrointestinal bacterial species
Patient acceptability of breath test
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Investigate whether exhaled breath can be used to detect and monitor esophageal cancer.Experimental Treatment1 Intervention
The procedures will include collecting participant's personal information and samples of participant's exhaled breath, urine, and saliva.
Find a Location
Who is running the clinical trial?
Benaroya Research InstituteLead Sponsor
49 Previous Clinical Trials
12,211 Total Patients Enrolled
Imperial College LondonOTHER
1,033 Previous Clinical Trials
15,024,540 Total Patients Enrolled
Donald E Low, MDPrincipal InvestigatorVirginia Mason Medical Center
1 Previous Clinical Trials
1,717 Total Patients Enrolled
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger