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Barrett's esophagus/erosive esophagitis for Acid Reflux
N/A
Waitlist Available
Research Sponsored by McGuire Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Summary
Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)
Eligible Conditions
- Acid Reflux
- Erosive Esophagitis
- Barrett's Esophagus
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Trial Design
3Treatment groups
Active Control
Placebo Group
Group I: Barrett's esophagus/erosive esophagitisActive Control3 Interventions
Patient's with Barrett's esophagus or with erosive esophagitis on endoscopy. Confocal endomicroscopy, endoscopic biopsies and mucosal impedance (MI) will be performed.
Group II: Non-erosive reflux disease (NERD)Active Control3 Interventions
Patient's with GERD refractory to PPI with no evidence of erosive esophagitis on endoscopy. Confocal endomicroscopy, endoscopic biopsies and mucosal impedance (MI) will be performed.
Group III: ControlPlacebo Group3 Interventions
Patient's with no h/o GERD or Barrett's esophagus who are undergoing endoscopy for non-GERD related indication. Confocal endomicroscopy, endoscopic biopsies and mucosal impedance (MI) will be performed.
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Who is running the clinical trial?
McGuire Research InstituteLead Sponsor
9 Previous Clinical Trials
321 Total Patients Enrolled
Hunter Holmes McGuire VA Medical CenterFED
10 Previous Clinical Trials
1,163 Total Patients Enrolled
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