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Insulin
Reduction of insulin basal rate 40 minutes prior to exercise for Diabetes
N/A
Waitlist Available
Led By Laurent Legault
Research Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 minutes (exercise period)
Awards & highlights
No Placebo-Only Group
All Individual Drugs Already Approved
Summary
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise. However, another potentially more efficient strategy to prevent exercise-induced hypoglycemia could be to reduce insulin basal rate a certain time prior to exercise. The objective of this study will be to compare the efficacy of two strategies to prevent exercise-induced hypoglycemia during a 60-minute exercise at moderate intensity: 1) reduce insulin basal rate 40 minutes prior to exercise; 2) reduce insulin basal rate 90 minutes prior to exercise.
Eligible Conditions
- Diabetes
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 60 minutes (exercise period)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes (exercise period)
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Glucose
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Trial Design
2Treatment groups
Active Control
Group I: Reduction of insulin basal rate 40 minutes prior to exerciseActive Control4 Interventions
Group II: Reduction of insulin basal rate 90 minutes prior to exerciseActive Control4 Interventions
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Who is running the clinical trial?
Institut de Recherches Cliniques de MontrealOTHER
70 Previous Clinical Trials
10,348 Total Patients Enrolled
McGill University Health Centre/Research Institute of the McGill University Health CentreLead Sponsor
470 Previous Clinical Trials
166,941 Total Patients Enrolled
Laurent LegaultPrincipal InvestigatorMontreal Children's Hospital of the MUHC
1 Previous Clinical Trials
28 Total Patients Enrolled
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