Popular Trials
OMT Intervention for Pregnancy
Recruiting1 award5 criteria
Saint Joseph, Michigan
Osteopathic Manipulative Therapy (OMT) is a hands-on approach to treating conditions that affect all areas of the body. Physicians trained in OMT (Doctors of Osteopathic Medicine or DO) use OMT to correct structural imbalances in the body, relieve pain, and improve circulation. Research shows that manual therapy is equally or more effective in treating pain and improving function versus oral analgesics (Bodine). OMT can decrease cost and improve function in patients with a minimal adverse effect profile. OMT applications include relieving asthma, irritable bowel syndrome, fibromyalgia, migraines, carpal tunnel syndrome, and sports-related injuries. In addition to the indications listed above, there is a growing body of research surrounding the use of OMT in pregnancy and its use in treatment and prevention of complications peripartum. Research Question: Does OMT during the third trimester of pregnancy improve delivery outcomes including: decreased labor times, less utilization of analgesics, fewer incidences of meconium fluid and perineal lacerations, and reduced risk of conversion to c-section or operative vaginal delivery? Though all research has shown that OMT is safe in pregnancy, there has been conflicting data on its benefits during the peripartum period. Additional research is needed to show its utility in decreasing labor times and need for analgesics during labor and reducing incidence of adverse outcomes including perineal lacerations and conversion to c-section and operative vaginal delivery. The current study will add to the growing body of knowledge about OMT during pregnancy and its potential benefits outside of musculoskeletal pain relief.
Neuromodulation
Non-Invasive Vagal Nerve Stimulation for Parkinson's Disease
Recruiting1 award4 criteria
Hines, Illinois
"This trial aims to improve gait and balance in Veterans with Parkinson's disease using a non-invasive neck stimulation technique. Gait disturbances are a major issue for these individuals and can lead to falls and
Behavioural Intervention
Timing of Breathing Tests for Patients on Ventilators
Recruiting1 award3 criteria
Chicago, Illinois
This trial aims to see how the timing of breathing tests affects recovery for ICU patients on ventilators. They will compare two timing strategies: one group will have the test early morning, while the other group
Popular Filters
Phase 3 Trials
Bile Acid Sequestrant
Maralixibat for Itching in Liver Disease
Recruiting1 awardPhase 3
Chicago, Illinois
This trial aims to find out if a new treatment called maralixibat is safe and works well for people with liver disease and itching that hasn't improved with other treatments and have no other options
Growth Hormone Receptor Agonist
Efruxifermin for Fatty Liver Disease
Recruiting1 awardPhase 3
South Bend, Indiana
"This trial will test the effectiveness of efruxifermin in treating liver cirrhosis caused by NASH/MASH in patients at multiple medical centers. It will be a randomized study where some participants
Trials With No Placebo
CAR T-cell Therapy
Rapcabtagene Autoleucel for Lupus Nephritis
Recruiting1 awardPhase 2
Chicago, Illinois
"This trial aims to compare the effectiveness and safety of rapcabtagene autoleucel with the standard treatment in patients with lupus and kidney inflammation that has not responded to standard treatment."
Procedure
Nerve Interface for Post-Mastectomy Pain
Recruiting1 award2 criteria
Chicago, Illinois
"This trial will investigate whether a nerve burying procedure called RPNI, done during mastectomy with immediate breast reconstruction surgery, can help prevent long-term nerve pain after breast cancer surgery. The study will involve
Perio-Healthy for Gum disease
Recruiting1 award1 criteria
Downers Grove, Illinois
The swelling of the gum, or periodontitis, is the leading cause for tooth loss, and currently affects up to 65 million adults only in the United States. One of the reasons for the widespread of periodontitis is because currently there are no definitive methods to detect the onset of gum disease. This lack of foresight impedes medical professionals to enact any preventive measures before the disease already manifests itself. We wish to expand our understanding towards the development of periodontitis by studying the expression and activity of salivary markers that have been associated with advanced stages of the disease, wherein the supporting tissues of tooth (periodontium) are already irreversibly destroyed. We hypothesize that a progressive shift in the expression of such salivary markers can indicate a change or evolution of periodontitis staging. In specific, we seek to establish a quantifiable relationship among levels of salivary proteases called MMPs, level of metal ions in different stages varying from health to periodontitis. The overall goal of this proposal is to enhance the predictability of periodontitis, as we are currently unable to diagnose the disease until the manifestation of its clinical signs and symptoms.
Behavioral Intervention
Digital Support for Inflammatory Bowel Disease
Recruiting1 award2 criteria
Chicago, Illinois
This trial aims to see if using a digital wellness app with artificial intelligence and virtual reality can provide mental health support to patients with inflammatory bowel disease and mild to moderate anxiety or depression. The study will assess
Anatomic Long Head of Biceps Tensioning Technique for Rotator Cuff Injury
Recruiting1 award2 criteria
Maywood, Illinois
The goal of this clinical trial is to determine the clinical impact of restoring the anatomic-tension relationship of the long head of the biceps (LHB) when performing a biceps tenotomy and tenodesis. The main question it aims to answer is whether anatomic tensioning will improve functional outcome scores and decrease postoperative complications. The investigators hypothesize that through a standardized method of anatomically tensioning the LHB tendon during tenodesis, patient outcomes will improve. Researchers will compare these outcomes to a control group receiving the traditional tensioning technique. Participants will be randomized to either the anatomic tensioning treatment group or the traditional tensioning control group.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.