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Uterine flushing for Infertility

N/A
Waitlist Available
Research Sponsored by CHU de Quebec-Universite Laval
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one month after randomisation

Summary

This trial is testing if washing the uterus with saltwater before ovulation can help women aged 18-37 who have unexplained infertility. The treatment might work by clearing out debris or changing inflammation in the uterus to make it easier to get pregnant.

Eligible Conditions
  • Infertility
  • Unexplained Infertility

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one month after randomisation
This trial's timeline: 3 weeks for screening, Varies for treatment, and one month after randomisation for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Proportion of participants with a live birth resulting from one cycle of treatment
Secondary study objectives
Adverse effects
Proportion of participants who find the intervention acceptable
Proportion of participants with a pregnancy resulting from one cycle of treatment

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Uterine flushingExperimental Treatment3 Interventions
Detection of ovulation, injection of 20 millilitres of physiological saline by an intra-uterine catheter the day of the luteinizing hormone surge, and sexual intercourse within 12 hours after intervention
Group II: Vaginal flushingPlacebo Group3 Interventions
Detection of ovulation, injection of 10 millilitres of physiological saline intravaginally the day of the luteinizing hormone surge, and sexual intercourse within 12 hours after intervention

Find a Location

Who is running the clinical trial?

CHU de Quebec-Universite LavalLead Sponsor
171 Previous Clinical Trials
109,413 Total Patients Enrolled
1 Trials studying Infertility
800 Patients Enrolled for Infertility
Sylvie Dodin, MD-MScStudy DirectorCentre Hospitalier Universitaire de Quebec
~19 spots leftby Nov 2025
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