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Probiotic

Greek yogurt exercising group (GYEX) for Inflammation

N/A
Waitlist Available
Research Sponsored by Brock University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Adults 55+ years from from the Niagara area.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weeks 0 and 8
Awards & highlights

Summary

This study aims to examine whether Greek yogurt (GY) consumption will lead to beneficial changes in bone metabolism and inflammation, in senior adults, male and female, when combined with regular exercise (senior fit classes; GYEX) and without exercise (GYNE). It is hypothesized that compared to a control group (senior fit classes, no GY; NYEX), an 8-week GY consumption intervention in senior adults with and without exercise will lead to positive effects on body composition, and markers of bone metabolism and inflammation such that the anabolic and anti-inflammatory markers of these physiological processes will increase more than any training-induced catabolic and pro-inflammatory markers (i.e., more than measures observed in the NYNE group).

Who is the study for?
This trial is for senior adults interested in the potential health benefits of Greek yogurt. Participants should be experiencing inflammation or osteoporosis and willing to consume Greek yogurt regularly. They must also be open to participating with or without accompanying regular exercise.
What is being tested?
The study tests if eating Greek yogurt can improve bone metabolism and reduce inflammation in seniors, comparing groups who exercise (GYEX), don't exercise (GYNE), and a control group that only exercises without yogurt (NYEX).
What are the potential side effects?
Greek yogurt is generally safe but may cause digestive discomfort, such as bloating or gas, especially in those with lactose intolerance or dairy sensitivity.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~weeks 0 and 8
This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 0 and 8 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Plasma concentrations of interleukin-10 (IL10)
Plasma concentrations of interleukin-6 (IL6)
Serum concentrations of C-telopeptides of type I collagen (CTX)
+9 more
Secondary study objectives
Body composition
Body mass
Energy intake and expenditure
+2 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Greek yogurt exercising group (GYEX)Experimental Treatment1 Intervention
Participants will be asked to consume 2 servings/day (preferably morning and night) of 175 g commercially available GY (0% MF, flavoured, 130 calories, 17 g protein, 225 g calcium (e.g., OIKOS High Protein GY) for a total of 8 weeks. For their convenience, the participants will be provided with appropriate scoops to measure out 175 g of GY per serving of the larger 650 g commercially available, pre-packaged containers. Although it is recommended to consume the two servings morning and night, to increase ecological validity and strengthen the feasibility of the intervention, the timing of the servings will be flexible to facilitate daily routines and lifestyles. For the same reasons, the participants will be able to choose the flavour of their GY.
Group II: Control exercising group (NYEX)Active Control1 Intervention
During the 8-weeks, participants will be instructed to follow their typical, habitual diet and exercise regimen.
Group III: Intervention non-exercising group (GYNE)Active Control1 Intervention
Participants will be instructed to follow their typical habitual diet. Participants will be asked to consume 2 servings/day (preferably morning and night) of 175 g commercially available GY (0% MF, flavoured, 130 calories, 17 g protein, 225 g calcium; e.g., OIKOS High Protein GY) for a total of 8 weeks. For their convenience, the participants will be provided with appropriate scoops to measure out 175 g of GY per serving of the larger 650 g commercially available, pre-packaged containers. Although it is recommended to consume the two servings morning and night, to increase ecological validity and strengthen the intervention's feasibility, the servings' timing will be flexible to facilitate daily routines and lifestyles. For the same reasons, the participants will be able to choose the flavour of their GY.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Greek yogurt
2011
N/A
~60

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Who is running the clinical trial?

Brock UniversityLead Sponsor
40 Previous Clinical Trials
6,479 Total Patients Enrolled
6 Trials studying Inflammation
158 Patients Enrolled for Inflammation
~40 spots leftby Nov 2026
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