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Factors Influencing Migraine in Adolescents

N/A
Recruiting
Led By Hadas Nahman-Averbuch, PhD
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Summary

This trial looks at physical, hormonal, and psychological factors that may cause migraines in teenage girls.

Who is the study for?
This trial is for boys and girls aged 10-13, with or without a family history of migraines. It includes those who have not been diagnosed with migraines but show symptoms, as well as those who've had migraines for over six months. Participants should not be on new preventative treatments.
What is being tested?
The study aims to understand factors predicting migraine onset and prognosis in adolescents by assessing pain responses, hormonal levels, brain activity through MRI scans, and how puberty status might influence these factors.
What are the potential side effects?
Since the interventions include assessments rather than medications (like neural assessments and pressure stimuli), side effects are minimal but may include discomfort from testing procedures like MRI or temporary pain from pressure stimuli.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Number of participants with a new diagnosis of migraine

Trial Design

2Treatment groups
Experimental Treatment
Group I: No Family History of MigraineExperimental Treatment10 Interventions
This group does not have a first or second degree relative diagnosed with migraine.
Group II: Family History of MigraineExperimental Treatment10 Interventions
This group has a first degree relative diagnosed with migraine.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MRI
2009
Completed Phase 2
~1620

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,362 Previous Clinical Trials
650,500 Total Patients Enrolled
8 Trials studying Migraine
1,242 Patients Enrolled for Migraine
Washington University School of MedicineLead Sponsor
1,970 Previous Clinical Trials
2,308,373 Total Patients Enrolled
1 Trials studying Migraine
100 Patients Enrolled for Migraine
Hadas Nahman-Averbuch, PhDPrincipal InvestigatorWashington University School of Medicine
3 Previous Clinical Trials
420 Total Patients Enrolled
1 Trials studying Migraine
100 Patients Enrolled for Migraine

Media Library

Family History of Migraine Clinical Trial Eligibility Overview. Trial Name: NCT05654012 — N/A
Migraine Research Study Groups: Family History of Migraine, No Family History of Migraine
Migraine Clinical Trial 2023: Family History of Migraine Highlights & Side Effects. Trial Name: NCT05654012 — N/A
Family History of Migraine 2023 Treatment Timeline for Medical Study. Trial Name: NCT05654012 — N/A
~167 spots leftby Mar 2028
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