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Exercise for Multiple Sclerosis

N/A
Recruiting
Led By Cameron Mang, PhD
Research Sponsored by University of Regina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks post intervention

Summary

This trial will compare the effects of different types of exercise on physical function, fitness, and central nervous system function in people with progressive MS.

Who is the study for?
This trial is for people with progressive multiple sclerosis (MS) who have moderate motor disability and can safely exercise. They should not be highly active already, haven't had an MS relapse in the last three months, and don't have other neurological conditions, psychiatric diagnoses or substance abuse issues.
What is being tested?
The study is testing how different types of exercises affect physical function, fitness, and central nervous system changes in individuals with MS. Participants will be assigned to one of three distinct exercise protocols to see which has the most beneficial effects.
What are the potential side effects?
Since this trial involves exercise programs rather than medication, side effects may include typical exercise-related discomforts such as muscle soreness or fatigue. However, specific risks depend on each participant's condition.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 weeks post intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 weeks post intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Timed 25-Foot Walk Test
Secondary study objectives
Motor Evoked Potential Amplitude
Other study objectives
9-Hole Pegboard Test
Brain
Mini Balance Evaluation Systems Test
+7 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Exercise Group 1Experimental Treatment1 Intervention
The intervention will focus on mobility and balance.
Group II: Exercise Group 2Active Control1 Intervention
This intervention will focus on physical fitness.
Group III: Exercise Group 3Placebo Group1 Intervention
This intervention will focus on flexibility, range of motion, and muscle tone.

Find a Location

Who is running the clinical trial?

University of ReginaLead Sponsor
55 Previous Clinical Trials
8,871 Total Patients Enrolled
First Steps Wellness CentreUNKNOWN
Saskatchewan Health Research FoundationOTHER
32 Previous Clinical Trials
5,065 Total Patients Enrolled

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT05496881 — N/A
Multiple Sclerosis Research Study Groups: Exercise Group 1, Exercise Group 2, Exercise Group 3
Multiple Sclerosis Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT05496881 — N/A
Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT05496881 — N/A
Multiple Sclerosis Patient Testimony for trial: Trial Name: NCT05496881 — N/A
~21 spots leftby Nov 2025
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