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Animal-Based Protein

Plant-Based vs Beef Protein for Obesity

N/A
Recruiting
Led By Bryant Keirns
Research Sponsored by Ball State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Not been diagnosed with a cardiometabolic conditions (e.g., type 2 diabetes)
Does not regularly take anti-inflammatory drugs (more than 2x week)
Must not have
Been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease)
Postmenopausal status (females only)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, up to 1 year.
Awards & highlights
No Placebo-Only Group

Summary

"This trial aims to compare the effects of a plant-based meat alternative (like Beyond Meat) with beef on factors like metabolism, digestion, and inflammation. The study will look at how these effects differ between

Who is the study for?
This trial is for individuals who are either of normal weight or have overweight/obesity. It aims to understand how a high-fat meal with plant-based protein (Beyond Meat) compares to one with animal protein (beef).
What is being tested?
The study tests the immediate effects on metabolism, digestion, and inflammation when participants consume a Western-style high-fat meal that includes either Beyond Meat or beef.
What are the potential side effects?
While not explicitly stated, potential side effects may include digestive discomfort or changes in metabolic markers due to the high-fat content of the meals being tested.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I do not have type 2 diabetes or similar heart-related conditions.
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I do not regularly take anti-inflammatory drugs more than twice a week.
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I do not take medication to lower my cholesterol.
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I have not been diagnosed with any heart diseases.
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I am a woman and have not gone through menopause.
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I am between 18 and 50 years old.
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I do not take medication to lower my blood sugar.
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I do not have a chronic inflammatory condition like rheumatoid arthritis or IBD.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have a chronic inflammatory condition like rheumatoid arthritis.
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I am a woman and have gone through menopause.
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I have been diagnosed with a heart condition.
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I regularly take anti-inflammatory drugs more than twice a week.
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I am taking medication to lower my cholesterol.
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I have been diagnosed with a condition like type 2 diabetes.
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I take medication to lower my blood sugar.
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I am younger than 18 or older than 50.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, up to 1 year.
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, up to 1 year. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Serum interleukin (IL)-6
Serum lipopolysaccharide
Serum lipopolysaccharide binding protein (LBP)
+2 more
Secondary study objectives
Glucose
HDL-C
Triglycerides
Other study objectives
Body composition
Systolic and diastolic pressure

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Meal Consumption with Beyond MeatExperimental Treatment1 Intervention
During the Beyond Meat arm, participants will consume a high-fat meal containing Beyond Meat (rather than beef). Meals will be otherwise identical.
Group II: Meal Consumption with BeefActive Control1 Intervention
During the Beef arm, participants will consume a high-fat meal containing beef (rather than Beyond Meat). Meals will be otherwise identical.

Find a Location

Who is running the clinical trial?

Ball State UniversityLead Sponsor
8 Previous Clinical Trials
612 Total Patients Enrolled
Bryant KeirnsPrincipal InvestigatorBall State University
1 Previous Clinical Trials
10 Total Patients Enrolled
~15 spots leftby Nov 2025
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