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REM sleep behaviour disorder for Dementia

N/A
Waitlist Available
Research Sponsored by Czech Technical University in Prague
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within one session (30 minutes)
Awards & highlights
No Placebo-Only Group

Summary

Speech is an important indicator of motor function and movement coordination and can be extremely sensitive to involvement in the course of neurologic diseases. The aim of this project is to discover for the first time using simple speech recording and high end pattern analysis preclinical stages of disabling central nervous system disorders including Parkinson's disease and other alpha-synucleinopathies in "at high risk" patients with REM sleep behavior disorder and thus provide one essential prerequisite for trials on REM sleep behavior disorder with preventive therapy.

Eligible Conditions
  • Dementia
  • REM Sleep Behavior Disorder
  • Parkinson's Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within one session (30 minutes)
This trial's timeline: 3 weeks for screening, Varies for treatment, and within one session (30 minutes) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Motor Speech Disorder Examination (MSDE)
Secondary study objectives
MDS Unified Parkinson's Disease Rating Scale (MDS-UPDRS)
Montreal Cognitive Assessment (MoCA)
SCOPA-AUT

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: REM sleep behaviour disorderExperimental Treatment2 Interventions
Speech assessment. Routine clinical assessment.
Group II: Parkinson's diseaseExperimental Treatment2 Interventions
Speech assessment. Routine clinical assessment.
Group III: Healthy controlsExperimental Treatment2 Interventions
Speech assessment. Routine clinical assessment.

Find a Location

Who is running the clinical trial?

Czech Technical University in PragueLead Sponsor
39 Previous Clinical Trials
2,380 Total Patients Enrolled
General University Hospital, PragueOTHER
54 Previous Clinical Trials
71,616 Total Patients Enrolled
Mayo ClinicOTHER
3,326 Previous Clinical Trials
3,059,132 Total Patients Enrolled
27 Trials studying Dementia
17,127 Patients Enrolled for Dementia
~41 spots leftby Nov 2025
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