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Motivation Skills Training for Serious Mental Illness (MST Trial)

N/A
Recruiting
Led By Alice Saperstein, PhD
Research Sponsored by Columbia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 months
Awards & highlights

Summary

This trial will compare two group therapies (MST and HBC) for adults with serious mental illness to help with motivation, goal attainment, and quality of life.

Who is the study for?
Adults aged 18-65 with schizophrenia or schizoaffective disorder, who speak English and are stable enough to attend outpatient therapy. They shouldn't have intellectual disabilities (IQ <70), severe recent substance use, or brain diseases due to neurological conditions.
What is being tested?
The trial is testing Motivation Skills Training (MST) against a Healthy Behaviors Control group in people with serious mental illness. Participants will attend weekly group sessions for about 12-14 weeks focusing on either motivation and self-regulation skills (MST) or physical health (HBC).
What are the potential side effects?
Since the interventions involve skill training and education rather than medication, typical drug side effects aren't expected. However, participants may experience stress or discomfort when discussing personal issues during therapy sessions.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Goal Attainment Scaling (GAS)
Motivation and Pleasure Scale (MAP)
Secondary study objectives
Heinrich's Quality of Life Scale (QLS)
Other study objectives
Barkley Deficits in Executive Functioning Scale - Short Form (BDEFS-SF)
Specific Levels of Functioning (SLOF)
Structured Clinical Interview for the Positive and Negative Syndrome Scale (SCI-PANSS)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Motivation Skills Training (MST)Experimental Treatment1 Intervention
MST is a weekly group-based skills training intervention that aims to improve knowledge about one's level and sources of motivation, the ability to monitor and regulate (understand and manage) motivation so that one can better initiate and sustain goal-directed behavior
Group II: Healthy Behaviors Control GroupActive Control1 Intervention
HBC is a weekly group-based intervention that provides psychoeducation and skills training to help individuals improve physical health

Find a Location

Who is running the clinical trial?

Columbia UniversityLead Sponsor
1,471 Previous Clinical Trials
2,536,270 Total Patients Enrolled
24 Trials studying Schizophrenia
3,246 Patients Enrolled for Schizophrenia
National Institute of Mental Health (NIMH)NIH
2,869 Previous Clinical Trials
2,777,456 Total Patients Enrolled
253 Trials studying Schizophrenia
89,844 Patients Enrolled for Schizophrenia
Alice Saperstein, PhDPrincipal InvestigatorColumbia University
1 Previous Clinical Trials
8 Total Patients Enrolled
1 Trials studying Schizophrenia
8 Patients Enrolled for Schizophrenia

Media Library

Motivation Skills Training Clinical Trial Eligibility Overview. Trial Name: NCT05805397 — N/A
Schizophrenia Research Study Groups: Motivation Skills Training (MST), Healthy Behaviors Control Group
Schizophrenia Clinical Trial 2023: Motivation Skills Training Highlights & Side Effects. Trial Name: NCT05805397 — N/A
Motivation Skills Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT05805397 — N/A
~53 spots leftby Oct 2025
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