← Back to Search

Procedure

Symphony Thrombectomy for Pulmonary Embolism

N/A
Recruiting
Research Sponsored by Imperative Care, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Clinical signs and symptoms consistent with acute PE.
Subject is between 18 and 80 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48 hours
Awards & highlights

Summary

This trial studied using a device to treat PE and found it to be safe and effective.

Who is the study for?
This trial is for adults aged 18-80 with recent pulmonary embolism (PE), confirmed by CTA, who have symptoms of PE and a stable blood pressure and heart rate. Participants must have an enlarged right ventricle but be in a stable condition to give consent and follow the study protocol.
What is being tested?
The Symphony Thrombectomy System is being tested for safety and effectiveness in removing blood clots from the lungs (pulmonary embolism). This device aims to improve cardiovascular health by treating these potentially life-threatening clots.
What are the potential side effects?
While specific side effects are not listed, thrombectomy procedures can generally cause bleeding, bruising at the catheter site, infection risk, or rare complications like injury to the blood vessels.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am showing signs of a possible pulmonary embolism.
Select...
I am between 18 and 80 years old.
Select...
My blood pressure is at least 90 mmHg and I have a heart condition where my right ventricle is enlarged.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Mean reduction of RV/LV ratio
Rate of major adverse events
Secondary study objectives
Rates of Major bleeding, device-related mortality, device-related clinical deterioration, device-related pulmonary vascular injury and device-related cardiac injury
Rates of PE related mortality, all-cause mortality, device-related SAEs and symptomatic PE recurrence

Trial Design

1Treatment groups
Experimental Treatment
Group I: Symphony Thrombectomy systemExperimental Treatment1 Intervention
Mechanical thrombectomy using the Symphony Thrombectomy system for the treatment of acute pulmonary embolism.

Find a Location

Who is running the clinical trial?

Imperative Care, Inc.Lead Sponsor
1 Previous Clinical Trials
328 Total Patients Enrolled
~54 spots leftby Mar 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top