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Low MAP Group for Traumatic Shock

N/A
Waitlist Available
Led By Matthew M Carrick, MD
Research Sponsored by Baylor College of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* All adult patients seen in the Ben Taub emergency center that have suffered a trauma, have a systolic blood pressure less than 90mm Hg, and are going to the operating room for a laparotomy or thoracotomy
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

The goal of this study will be to determine if a lower than normal blood pressure during surgery for bleeding in the abdomen or chest will result in decreased bleeding and decreased chance of death.

Eligible Conditions
  • Traumatic Shock
  • Multiple Injuries
  • Penetrating Wounds
  • Trauma
  • Hemorrhagic Shock
  • Multiple Trauma

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Low MAP GroupExperimental Treatment1 Intervention
Hypotensive Group with a target minimum MAP of 50 mmHg
Group II: High MAP groupActive Control1 Intervention
Non experimental group: These patients will have a target minimum MAP of 65 mm Hg

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Who is running the clinical trial?

Baylor College of MedicineLead Sponsor
1,022 Previous Clinical Trials
6,029,149 Total Patients Enrolled
Matthew M Carrick, MDPrincipal InvestigatorBaylor College of Medicine
~15 spots leftby Nov 2025
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