Popular Trials
Neuromodulation
Cereset for Dementia Caregiver Stress
This trial tests if Cereset, a sound-based brain therapy, can help caregivers of people with dementia who are stressed or anxious. The therapy aims to improve how their heart responds to stress by balancing brain activity.
Behavioural Intervention
Bioboosti Device for Insomnia
This trial is testing the Bioboosti device, a gadget to help people with insomnia sleep better without medication. The study involves patients diagnosed with insomnia to see if this device can improve their sleep quality. The Bioboosti device has been previously tested, showing improved sleep quality and reduced insomnia symptoms after a short period of use.
Behavioral Intervention
Online Cognitive Behavioural Therapy for Insomnia
This trial is testing a new online program to help people with insomnia and memory problems. The study wants to know if this program can improve sleep quality, mental health, and cognitive abilities compared to a control
Popular Filters
Trials for Chronic Insomnia Patients
Behavioural Intervention
CBT + Trazodone for Insomnia
This trial aims to compare how individuals with insomnia and short sleep duration differ from those with normal sleep duration in terms of health risks and response to treatment. The study will investigate the effectiveness of two common insomnia
MBSR treatment for Traumatic Brain Injury
To evaluate the effects of Mindfulness Based Stress Reduction (MBSR) as an adjunct to usual clinical care for treatment of stress and chronic insomnia for patients with mild to moderate traumatic brain injury (MTBI). MBSR is a standardized protocol of meditation and yoga that has been studied extensively in other populations, however the effects of MBSR have not yet been well studied in the proposed population of service members with a Traumatic Brain Injury (TBI) who are experiencing insomnia.
Trials for Depression Patients
Behavioral Intervention
Digital CBT for Insomnia and Depression
This trial will test whether treating insomnia first, then depression, is better than treating depression first, or treating either one alone. It will also try to find out if there's a difference in how well different people respond to different treatments.
Behavioral Intervention
EFT for Cancer-related Anxiety and Depression
This trial teaches cholangiocarcinoma patients a technique called EFT through online coaching to help reduce anxiety and depression. The study aims to see if this method can improve their mental health and quality of life. Participants' symptoms are measured at different stages of the coaching process. EFT (Emotional Freedom Techniques) has been studied as a treatment for anxiety, depression, and stress in various populations, including nursing students and individuals with chronic conditions.
Suvorexant for Insomnia
Depression with ongoing insomnia is a common clinical presentation with patients. Clinical data suggests that patients with insomnia that receive concomitant treatment with a sleep aid experience a more robust antidepressant response along with a quicker response. The purpose of this clinical study is to compare the effectiveness of the FDA-approved insomnia medication suvorexant, also known as Belsomra®, as add-on treatment to an antidepressant to that of placebo plus antidepressant treatment in patients with depression and residual or ongoing insomnia.
Selective Serotonin Reuptake Inhibitor
Escitalopram for Insomnia
Preliminary studies suggest that the response to antidepressant medication can be accelerated by targeting insomnia with adjunctive use of eszopiclone. It is not yet known what mechanism(s) support this acceleration in response, though preliminary findings support the hypothesis that early restoration of sleep may facilitate BDNF-based effects of antidepressant medications. The optimal duration of co-treatment is also unknown. This study will test specific hypotheses about brain mechanisms and evaluate the effects of continued eszopiclone beyond the time window when response acceleration should be observed.
1 for Insomnia
This study is a randomized clinical trial to test the efficacy of Cognitive-Behavioral Insomnia Therapy when used in isolation or in combination with antidepressant medication (escitalopram) among patients with Major depressive disorder and insomnia.
Trials With No Placebo
Behavioural Intervention
Temperature-Regulating Therapy for Insomnia in Tourette Syndrome
This trial tests a forehead temperature-regulating device to help adults with Tourette's disorder sleep better. The device adjusts forehead temperature to improve brain function and sleep quality.
Behavioral Intervention
Digital CBT for Insomnia and Depression
This trial will test whether treating insomnia first, then depression, is better than treating depression first, or treating either one alone. It will also try to find out if there's a difference in how well different people respond to different treatments.
Behavioral Intervention
EMPOWER-ED App for Benzodiazepine Withdrawal
This trial tests an app called EMPOWER-ED designed to help Veterans reduce or stop using anxiety medications like Ativan and Xanax. The app offers step-by-step support to taper off these drugs safely. Researchers hope it will improve health outcomes and reduce risks associated with long-term use of these medications.
Behavioural Intervention
Bright Light Therapy for Sleep Disorders in Multiple Sclerosis
This trial tests if bright light therapy can safely and effectively reduce sleep disturbances in people with multiple sclerosis by helping reset their internal body clock. Bright light therapy has been explored for daytime sleepiness and insomnia in patients with Parkinson's disease and other conditions, showing potential benefits.
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Frequently Asked Questions
Introduction to insomnia
What are the top hospitals conducting insomnia research?
When it comes to tackling the complex issue of insomnia, top hospitals across the United States are actively engaged in clinical trials to find innovative solutions. In Philadelphia, the University of Pennsylvania is leading the way with four ongoing insomnia trials. Known for its cutting-edge research and expertise, this institution aims to improve sleep quality and address the underlying causes of this prevalent condition. Meanwhile, on the West Coast in Palo Alto, California, the VA Palo Alto Health Care System is making strides with three active insomnia trials. Collaborating closely with veterans who often face sleep disturbances as a result of various factors, this hospital seeks to enhance their well-being through groundbreaking treatments.
In Charlottesville, Virginia, researchers at the University of Virginia are also dedicated to unraveling mysteries surrounding insomnia by conducting three active clinical trials. With an emphasis on understanding individual differences in sleep patterns and tailoring interventions accordingly, they strive towards personalized medicine in treating this common disorder.
Similarly committed to advancing our knowledge about effective approaches against insomnia is San Francisco's own San Francisco VA Medical Center. Their current focus lies within three ongoing clinical trials aimed at identifying novel therapies that can help individuals obtain restorative sleep.
Not far from there—located at Columbia—is another key player in these efforts: The University of Missouri—a hub where scientists conduct research while simultaneously running three promising active insomnia-related studies aiming for amelioration via tailor-made remedies catering differing subjective predicaments faced by each insomniac
These esteemed institutions represent beacons of hope for those affected by chronic sleeplessness. By delving into new avenues through rigorous scientific investigations and patient collaboration nationwide , they offer prospects for improved diagnosis methods as well as more efficient treatment options that may ultimately grant many a good night's rest
Which are the best cities for insomnia clinical trials?
When it comes to insomnia clinical trials, several cities stand out as leaders in research and development. Boston, Massachusetts leads the way with 9 active trials exploring treatments like Bioboosti, Sleep ALL Night, and suvorexant. Philadelphia, Pennsylvania closely follows with 8 ongoing studies focused on interventions such as Sleep Hygiene and Solriamfetol+ CBT-I. Tucson, Arizona and San Francisco, California both offer 7 active trials addressing various approaches like In-person CBTi and Apnea and Insomnia Relief (AIR). Lastly, Baltimore, Maryland conducts 6 active trials examining strategies including Cognitive-Behavioral Therapy for Insomnia (CBT-I) and Light therapy. These cities provide individuals struggling with insomnia access to cutting-edge clinical trials that may pave the way for effective treatment options in the future.
Which are the top treatments for insomnia being explored in clinical trials?
Insomnia research is actively investigating various treatments to alleviate this sleep disorder. Among the top contenders in clinical trials are:
- Tasimelteon: Currently undergoing testing in two active trials for insomnia.
- Suvorexant: Garnering attention with three ongoing clinical trials focused on treating insomnia.
- Ramelteon: Being explored as a potential solution for insomnia, with one active trial dedicated to its evaluation. These promising treatments offer hope for individuals struggling with insomnia and may bring new possibilities for better sleep quality and overall well-being.
What are the most recent clinical trials for insomnia?
Recent clinical trials have brought forth promising developments in the field of insomnia treatment. One notable study explored a new therapeutic approach for insomnia, while another investigated the combination of solriamfetol and cognitive-behavioral therapy for insomnia (CBT-I). Additionally, researchers examined the effectiveness of pimavanserin when administered at a dose of 34mg orally before bedtime. Another trial focused on evaluating SHUTi OASIS, an intervention designed to address insomnia-related concerns. Lastly, suvorexant was studied as a potential treatment option for individuals suffering from insomnia. These innovative trials offer hope for improved management and relief from this sleep disorder.
What insomnia clinical trials were recently completed?
Several recent clinical trials have investigated potential treatments for insomnia, a common sleep disorder that affects many individuals. These trials aimed to address the challenges of insomnia and enhance our understanding of effective interventions. While specific trial details vary, notable completed studies include investigations into both pharmacological and non-pharmacological approaches. By focusing on this important area of research, scientists are working towards improving the quality of life for those affected by insomnia.