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Cell phone intervention arm for Latent Tuberculosis Infection

Phase < 1
Waitlist Available
Led By Dr. Richard Lester, MD
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 or 9 months
Awards & highlights
No Placebo-Only Group

Summary

This study will examine the impact of use of mobile phones and text messaging on adherence to treatment for patients with latent TB infection. Half (50%) of the 350 anticipated study participants will receive weekly text messages inquiring on their health status in relation to their prescribed treatment, while the other half (50%) will not receive weekly text messages at all. Medical adherence will be assessed by monthly blood-work, clinic visits and by interviewing patients at each of these visits. The investigators hypothesis is that enhanced communication with a health care provider, via a structured cell phone SMS text messaging based program (WelTel), will result in a 15% improvement in the proportion of patients who successfully complete their LTBI treatment regimens.

Eligible Conditions
  • Latent Tuberculosis Infection

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 or 9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 or 9 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Successful completion of LTBI treatment regimens.

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cell phone intervention armExperimental Treatment1 Intervention
Upon consent, participants will be randomly assigned to receive either 1) standard of care (9 months of INH or 4 months of RIF) and weekly SMS text messages via mobile phone or 2) standard of care (9 months of INH or months of RIF) without weekly SMS text messages via mobile phone.
Group II: Non-interventionActive Control1 Intervention
Participants will only receive standard of care

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,465 Previous Clinical Trials
2,485,147 Total Patients Enrolled
British Columbia Cancer AgencyOTHER
175 Previous Clinical Trials
93,878 Total Patients Enrolled
Dr. Richard Lester, MDPrincipal InvestigatorUniversity of British Columbia
~26 spots leftby Nov 2025