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Arista for Blood Loss

Phase 1
Waitlist Available
Research Sponsored by Virtua Health, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months post op
Awards & highlights
No Placebo-Only Group

Summary

This trial tests if using Arista MPH® powder during knee replacement surgery can reduce blood loss and improve recovery. It targets patients with osteoarthritis needing knee surgery. The powder helps blood clot faster, reducing bleeding and aiding healing.

Eligible Conditions
  • Surgical Blood Loss
  • Blood Loss

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months post op
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months post op for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Blood Loss
Secondary study objectives
Range of Motion
Thigh Circumference

Side effects data

From 2023 Phase 1 trial • 61 Patients • NCT05522153
10%
Readmission due to pain
6%
Infection
100%
80%
60%
40%
20%
0%
Study treatment Arm
Arista Group
Control Group

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Arista groupExperimental Treatment1 Intervention
this group of randomized patients will receive 5 grams of arista hemostatic powder intra-operatively in their wound in addition to 1 gram of IV transexemic acid prior to incision
Group II: control groupActive Control1 Intervention
this group of randomized patients will receive just the 1 gram of IV transexemic acid prior to incision
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Arista
2021
Completed Phase 1
~130

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Virtua Health, Inc.Lead Sponsor
9 Previous Clinical Trials
626 Total Patients Enrolled
Becton, Dickinson and CompanyIndustry Sponsor
75 Previous Clinical Trials
90,366 Total Patients Enrolled
~14 spots leftby Nov 2025
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