← Back to Search

Imaging Speech for Cerebellar Stroke

N/A
Waitlist Available
Led By Jason W Bohland, Ph.D.
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Cohort 1 (neurotypical adults): Age 18-49, Right-handed, Native English speaker
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up first session lasting 2-3 hours, within 12 months of enrollment
Awards & highlights

Summary

"This trial aims to understand how the brain areas responsible for movement interact with those involved in hearing and perceiving speech in healthy adults and individuals who have had cerebellar strokes. They will investigate changes in

Who is the study for?
This trial is for adults who speak normally and those who have had a stroke affecting the cerebellum, which is part of the brain that helps coordinate movement. Participants should be willing to undergo various speech tests and non-invasive brain imaging like EEG and fMRI.
What is being tested?
The study investigates how different brain areas involved in planning, controlling movements, hearing, and perceiving speech work together. It involves auditory tests, monitoring neural responses during speech tasks, learning behaviors, silent articulation response tracking, and comparing self-generated versus external speech processing.
What are the potential side effects?
Since this study uses non-invasive methods such as EEG and fMRI for imaging the brain's activity related to speech functions there are minimal side effects expected. However minor discomforts from wearing EEG caps or lying still in an MRI machine may occur.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18-49 years old, right-handed, and a native English speaker.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one session lasting 2-3 hours, within 12 months of enrollment
This trial's timeline: 3 weeks for screening, Varies for treatment, and one session lasting 2-3 hours, within 12 months of enrollment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
BOLD responses during adaptation to auditory perturbations
BOLD responses during learning of non-speech auditory motor targets
BOLD responses related to pre-speech auditory modulation
+3 more
Secondary study objectives
Auditory acuity
BOLD responses to silent articulation task
BOLD responses to speech listening task
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Speech behavior and functional imagingExperimental Treatment9 Interventions
Assessing the neural correlates of speaking-induced sensory modulation in all three cohorts using behavior and neuroimaging tasks in up to 6 sessions.

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,762 Previous Clinical Trials
16,347,903 Total Patients Enrolled
Northwestern UniversityOTHER
1,625 Previous Clinical Trials
937,189 Total Patients Enrolled
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
348 Previous Clinical Trials
180,637 Total Patients Enrolled
~67 spots leftby Jul 2028
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top