← Back to Search

Orthopedic Implant

Knee Replacement Systems for Osteoarthritis

N/A
Recruiting
Led By James Nace, MD
Research Sponsored by LifeBridge Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subject is male or non-pregnant female aged between 18 and 75 years of age.
Subject is male or non-pregnant female aged between 18 and 75 years of age
Must not have
Subject has a diagnosis of avascular necrosis or inflammatory arthritis
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-operative; post-operative - 6 week, 6 month, 12 month, 24 month, 36 month, and 60 month follow-up visit
Awards & highlights

Summary

This trial is comparing two types of knee replacements to see which works better for patients with degenerative joint disease.

Who is the study for?
This trial is for men and non-pregnant women aged 18-75 who need a knee replacement due to degenerative joint disease. They must be able to walk, attend follow-up visits, and not have had previous knee replacements or conditions that would affect walking tests.
What is being tested?
The study compares two types of knee implants: the MicroPort Evolution Medial-Pivot Knee System and the Stryker Triathlon Tritanium Knee System. It will assess which design better improves pain relief, function, and patient satisfaction after surgery.
What are the potential side effects?
Potential side effects from total knee replacement may include pain at the surgery site, swelling, stiffness in the knee joint, infection risk at the wound site or within the new joint.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am a man or a non-pregnant woman aged 18 to 75.
Select...
I am a man or a non-pregnant woman aged 18 to 75.
Select...
I am approved for a total knee replacement using specific knee implants.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have been diagnosed with avascular necrosis or inflammatory arthritis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~operative visit; post-operative - 6 week, 6 month, 12 month, 24 month, 36 month, and 60 month follow-up visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and operative visit; post-operative - 6 week, 6 month, 12 month, 24 month, 36 month, and 60 month follow-up visit for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in Active and Passive Range of Motion
Change in Anterior/Posterior Knee Translation
Change in Five Times Sit to Stand Test
+7 more
Secondary study objectives
Change in Forgotten Joint Score FJS
Knee
Knee
+4 more

Trial Design

2Treatment groups
Active Control
Group I: Single Radius Design Total Knee SystemActive Control1 Intervention
Total Knee Arthroplasty will be done by implanting the Stryker Triathlon Tritanium Knee System into subjects.
Group II: Medial-Pivot Knee SystemActive Control1 Intervention
Total Knee Arthroplasty will be done by implanting the MicroPort Medial Pivot Knee System into subjects.

Find a Location

Who is running the clinical trial?

MicroPort Orthopedics Inc.Industry Sponsor
31 Previous Clinical Trials
3,386 Total Patients Enrolled
7 Trials studying Osteoarthritis
592 Patients Enrolled for Osteoarthritis
LifeBridge HealthLead Sponsor
28 Previous Clinical Trials
4,268 Total Patients Enrolled
2 Trials studying Osteoarthritis
539 Patients Enrolled for Osteoarthritis
Rubin Institute for Advanced OrthopedicsUNKNOWN
1 Previous Clinical Trials
78 Total Patients Enrolled

Media Library

MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting) (Orthopedic Implant) Clinical Trial Eligibility Overview. Trial Name: NCT04814082 — N/A
Osteoarthritis Research Study Groups: Single Radius Design Total Knee System, Medial-Pivot Knee System
Osteoarthritis Clinical Trial 2023: MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting) Highlights & Side Effects. Trial Name: NCT04814082 — N/A
MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting) (Orthopedic Implant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04814082 — N/A
~22 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top