Trials in Boston, Massachusetts
Here are the top 10 medical studies for depression in Boston, Massachusetts
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Phase 3 Trials
Psychedelic
Psilocybin for Treatment-Resistant Depression
Recruiting1 awardPhase 3
North Worcester, Massachusetts
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
NMRA-335140 for Depression
Recruiting2 awardsPhase 3
Boston, Massachusetts
This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.
Behavioural Intervention
NMRA 335140 for Depression
Recruiting1 awardPhase 3
Watertown, Massachusetts
This trial tests a drug (NMRA 335140) for symptoms of depression in people with Major Depressive Disorder. It has a screening period, a 6-week treatment period with either the drug or placebo, and an extension study.
Trials With No Placebo
Behavioural Intervention
Wraparound Intervention for Families with Substance Use Disorders
Recruiting1 award
Claremont, New Hampshire
This trial is testing whether the Wraparound intervention can help families with substance use disorders who have children placed outside the home or are at risk of such placement. The investigators hypothesize that families receiving Wraparound will have better parenting and family functioning outcomes, child safety, permanency, and well-being, and parental recovery than families receiving treatment as usual.
Behavioral Intervention
Mental and Physical Health Intervention for Preventing Disability in Minority Elders
Recruiting1 award4 criteria
Boston, Massachusetts
This trial tests a program called Positive Minds-Strong Bodies Enhanced (PMSB-E) for older adults from minority groups. The program combines mental health support and physical exercise to help improve their overall well-being. It includes sessions to change negative thoughts and group exercises to build strength, all conducted in community settings. Positive-Minds-Strong Bodies (PM-SB) aims to reduce mental and physical disability for minority and immigrant elders through mental health support and physical exercise.
Behavioural Intervention
Buspirone + Melatonin for Depression After Traumatic Brain Injury
Recruiting3 awardsPhase 4
Charlestown, Massachusetts
This trial is investigating the effectiveness of a novel treatment combination of Buspirone and Melatonin (B+MEL) in outpatients with clinical depression who have also suffered a traumatic brain injury (TBI). The trial will measure changes in depressive symptoms, cognitive symptoms, and brain activity before and after treatment.
Behavioral Intervention
Chronotherapy for Perinatal Depression
Recruiting1 award
Providence, Rhode Island
This trial is testing whether a non-pharmacological treatment called Personalized Integrated Chronotherapy (PIC) can improve outcomes for pregnant women with depression and anxiety. The study will enroll expectant mothers who will be randomized to either: (a) usual care (UC, n = 110) or (b) PIC+UC (n = 110). PIC+UC will have pregnancy and postpartum components and will be administered via a personalized approach tailored to optimize the intervention based on each patient's individual circadian and sleep timing. The study will assess whether PIC is effective in improving mood symptoms and will also examine the target mechanisms by which
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.