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Nonsteroidal Anti-inflammatory Drug
Salsalate Oral Tablet for Prophylaxis of Preeclampsia
Phase < 1
Waitlist Available
Led By Anna Stanhewicz, PhD
Research Sponsored by University of Iowa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment
Summary
This trial is investigating why women who develop preeclampsia during pregnancy are more likely to develop cardiovascular disease later in life, in order to identify better clinical management of cardiovascular disease risk in these women.
Eligible Conditions
- Prophylaxis of Preeclampsia
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~a total of 3 times throughout the study (approximately 4 weeks): 1) at the beginning of the study, 2) at the completion of the 5 day placebo treatment, and 3) at the completion of 5 days of oral salsalate treatment
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
change in endothelial function following salsalate treatment compared to placebo treatment
Secondary study objectives
change in inflammatory response to ang II compared to baseline
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: SalsalateExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention
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Who is running the clinical trial?
Penn State UniversityOTHER
368 Previous Clinical Trials
127,559 Total Patients Enrolled
University of IowaLead Sponsor
465 Previous Clinical Trials
893,239 Total Patients Enrolled
Anna Stanhewicz, PhDPrincipal Investigator - University of Iowa
University of Iowa
3 Previous Clinical Trials
74 Total Patients Enrolled
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